human CCDC6 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CCDC6.
shAAV-204342
AAV-h-CCDC6-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CCDC6 (coiled-coil domain containing 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
coiled-coil domain-containing protein 6; D10S170; H4; papillary thyroid carcinoma-encoded protein; Protein H4; PTC; TPC; TST1
Description (eCommerce)
CCDC6 is the product of the H4(D10S170) gene identified as a gene that exhibits frequent rearrangement with RET in papillary thyroid tumors.
Description (Vector)
CCDC6 encodes a coiled-coil domain-containing protein. The encoded protein is ubiquitously expressed and may function as a tumor suppressor. A chromosomal rearrangement resulting in the expression of a fusion gene containing a portion of this gene and the intracellular kinase-encoding domain of the ret proto-oncogene is the cause of thyroid papillary carcinoma.
Gene ID
8030
Gene Name (eCommerce)
coiled-coil domain containing 6
Gene Name (Vector)
coiled-coil domain containing 6
Gene Symbol
CCDC6
HGNC ID
HGNC:18782
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1425
ORF Size (bp)
1425 bp
Protein Name (eCommerce)
Coiled-coil domain-containing protein 6
RefSeq ID
NM_005436
RefSeq Synonyms
NM_005436, BC064391, BC036757,
Research Areas
Cancer,Cytoskeleton,DNA Damage/Repair
Research Areas (Faceted)
cancer,cell_biology,genetics,transcription_translation
Species
human
Target Sentence
CCDC6 is the product of the H4(D10S170) gene identified as a gene that exhibits frequent rearrangement with RET in papillary thyroid tumors.
UniGene ID
Hs.591360
UniProt ID (eCommerce)
Q16204
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.