mouse SETDB2 Adenovirus

Name 
Ad-m-SETDB2
Cat No 
ADV-271765
Availability
4-5 weeks

This is an Adenovirus expressing Mouse SETDB2.

ADV-271765
Ad-m-SETDB2

Ready-to-use Adenovirus expressing Mouse SETDB2 (SET domain, bifurcated 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Clld8; Gm293; KMT1F;
Description (Vector)
Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis.
Gene ID
239122
Gene Name (Vector)
SET domain, bifurcated 2
Gene Symbol
SETDB2
ORF Size (aa)
2094
ORF Size (bp)
2094 bp
RefSeq ID
NM_001081024
RefSeq Synonyms
NM_001320721, NM_001320720, NM_001081024, BC172021, BC157926,
Species
mouse
UniGene ID
Mm.390729

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.