mouse SETDB2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse SETDB2.
shAAV-271765
AAV-m-SETDB2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse SETDB2 (SET domain, bifurcated 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Clld8; Gm293; KMT1F;
Description (Vector)
Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis.
Gene ID
239122
Gene Name (Vector)
SET domain, bifurcated 2
Gene Symbol
SETDB2
ORF Size (aa)
2094
ORF Size (bp)
2094 bp
RefSeq ID
NM_001081024
RefSeq Synonyms
NM_001320721, NM_001320720, NM_001081024, BC172021, BC157926,
Species
mouse
UniGene ID
Mm.390729
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.