mouse SCN5A Adenovirus

Name
Ad-m-SCN5A

Cat No
ADV-271451

Availability
4-5 weeks

This is an Adenovirus expressing Mouse Scn5a.

ADV-271451

Ad-m-SCN5A

Ready-to-use Adenovirus expressing Mouse Scn5a (sodium channel, voltage-gated, type V, alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

mH1; Nav1.5; Nav1.5c; SkM1; SkM2

Description (Vector)

This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant Na(+) channel isoform. This channel is responsible for the initial upstroke of the action potential. Channel inactivation is regulated by intracellular calcium levels.

Gene ID

20271

Gene Name (Vector)

sodium channel, voltage-gated, type V, alpha

Gene Symbol

Scn5a

ORF Size (aa)

6063

ORF Size (bp)

6063 bp

RefSeq ID

NM_021544

RefSeq Synonyms

NM_021544, NM_001253860, BC172643,

Species

mouse

UniGene ID

Mm.103584

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.