mouse RBM25 Adenovirus
This is an Adenovirus expressing Mouse Rbm25.
ADV-270240
Ad-m-RBM25
Ready-to-use Adenovirus expressing Mouse Rbm25 (RNA binding motif protein 25). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2600011C06Rik; 2610015J01Rik; A130095G20Rik; AI159652; AL023075; AU043498; RNPC7
Description (Vector)
RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5'-splice site (5'-ss) selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5'-ss usage through the 5'-CGGGCA-3' RNA sequence. Its association with LUC7L3 promotes U1 snRNP binding to a weak 5' ss in a 5'-CGGGCA-3'-dependent manner. Binds to the exonic splicing enhancer 5'-CGGGCA-3' RNA sequence located within exon 2 of the BCL2L1 pre-mRNA.
Gene ID
67039
Gene Name (Vector)
RNA binding motif protein 25
Gene Symbol
Rbm25
ORF Size (aa)
2526
ORF Size (bp)
2526 bp
RefSeq ID
NM_027349
RefSeq Synonyms
NM_027349, BC158104,
Species
mouse
UniGene ID
Mm.46005
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.