mouse NUMB Adenovirus

Name
Ad-m-NUMB

Cat No
ADV-266207

Availability
4-5 weeks

This is an Adenovirus expressing Mouse Numb.

ADV-266207

Ad-m-NUMB

Ready-to-use Adenovirus expressing Mouse Numb (numb homolog (Drosophila)). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

Description (Vector)

Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.

Gene ID

18222

Gene Name (Vector)

numb homolog (Drosophila)

Gene Symbol

Numb

ORF Size (aa)

1782

ORF Size (bp)

1782 bp

RefSeq ID

NM_010949

RefSeq Synonyms

NM_010949, NM_001272056, NM_001272055, NM_001136075, BC033459,

Species

mouse

UniGene ID

Mm.4390

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.