human C3ORF37 Over-expression AAV

Name
AAV-h-C3ORF37

Cat No
AAV-203399

Availability
4-5 weeks

This is an AAV expressing Human HMCES.

AAV-203399

AAV-h-C3ORF37

Ready-to-use AAV expressing Human HMCES (5-hydroxymethylcytosine (hmC) binding, ES cell-specific). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

5-hydroxymethylcytosine (hmC) binding, ES cell-specific; C3orf37; DC12; embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein; ES cell-specific 5hmC-binding protein; putative peptidase SRAPD1; SOS response associated peptidase domain containing 1; SRAP domain-containing protein 1; SRAPD1; UPF0361 protein C3orf37

Description (eCommerce)

HMCES specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells, suggesting that it acts as a specific reader of 5hmC in stem cells (By similarity)Â [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96FZ2].

Gene ID

56941

Gene Name (eCommerce)

5-hydroxymethylcytosine binding, ES cell specific

Gene Name (Vector)

5-hydroxymethylcytosine (hmC) binding, ES cell-specific

Gene Symbol

HMCES

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1065

ORF Size (bp)

1065 bp

Protein Name (eCommerce)

Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein

RefSeq ID

NM_020187

RefSeq Synonyms

NM_020187, NM_001006109, BC088363, BC050686, BC010125, BC009993,

Research Areas

Cell Biology

Research Areas (Faceted)

cell_biology

Species

human

Target Sentence

HMCES specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells, suggesting that it acts as a specific reader of 5hmC in stem cells (By similarity)Â [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96FZ2].

UniGene ID

Hs.458320

UniProt ID (eCommerce)

Q96FZ2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.