human C2ORF64 Over-expression AAV
This is an AAV expressing Human COA5.
AAV-203327
AAV-h-C2ORF64
Ready-to-use AAV expressing Human COA5 (cytochrome c oxidase assembly factor 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
6330578E17Rik; C2orf64; CEMCOX3; Pet191
Description (Vector)
COA5 encodes an ortholog of yeast Pet191, which in yeast is a subunit of a large oligomeric complex associated with the mitochondrial inner membrane, and required for the assembly of the cytochrome c oxidase complex. Mutations in this gene are associated with mitochondrial complex IV deficiency, a disorder of the mitochondrial respiratory chain with heterogeneous clinical manifestations, ranging from isolated myopathy to a severe disease affecting several tissues and organs.
Gene ID
493753
Gene Name (Vector)
cytochrome c oxidase assembly factor 5
Gene Symbol
COA5
HGNC ID
HGNC:33848
ORF Size (aa)
225
RefSeq ID
NM_001008215
RefSeq Synonyms
NM_001008215, BC047722,
Species
human
UniGene ID
Hs.596537
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.