human C22ORF28 Over-expression AAV

Name
AAV-h-C22ORF28

Cat No
AAV-203266

Availability
4-5 weeks

This is an AAV expressing Human RTCB.

AAV-203266

AAV-h-C22ORF28

Ready-to-use AAV expressing Human RTCB (RNA 2′,3′-cyclic phosphate and 5′-OH ligase). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ankyrin repeat domain 54; C22orf28; DJ149A16.6; FAAP; focal adhesion-associated protein; HSPC117; tRNA-splicing ligase RtcB homolog

Description (eCommerce)

RTCB encodes tRNA-splicing ligase RtcB homolog, the catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs. tRNA-splicing ligase RtcB homolog may also act as an RNA ligase with broad substrate specificity, and may function toward other RNAs [taken from UniProtKB (Entry: Q9Y3I0)].

Gene ID

51493

Gene Name (eCommerce)

RNA 2',3'-cyclic phosphate and 5'-OH ligase

Gene Name (Vector)

RNA 2',3'-cyclic phosphate and 5'-OH ligase

Gene Symbol

RTCB

HGNC ID

HGNC:26935

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1518

ORF Size (bp)

1518 bp

Protein Name (eCommerce)

tRNA-splicing ligase RtcB homolog

RefSeq ID

NM_014306

RefSeq Synonyms

NM_014306, BC016707, BC010308, BC002970, BC000151,

Research Areas

RNA Processing

Research Areas (Faceted)

cell_biology,genetics,transcription_translation

Species

human

Target Sentence

RTCB encodes tRNA-splicing ligase RtcB homolog, the catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs. tRNA-splicing ligase RtcB homolog may also act as an RNA ligase with broad substrate specificity, and may function toward other RNAs [taken from UniProtKB (Entry: Q9Y3I0)].

UniGene ID

Hs.474643

UniProt ID (eCommerce)

Q9Y3I0

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.