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human C14ORF133 Over-expression AAV

Name 
AAV-h-C14ORF133
Cat No 
AAV-202632
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human VIPAS39.

AAV-202632
AAV-h-C14ORF133

Ready-to-use AAV expressing Human VIPAS39 (VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C14orf133; hSPE-39; SPE39; SPE-39; spermatogenesis-defective protein 39 homolog; VIPAR; VPS16B; VPS33B-interacting protein in apical-basolateral polarity regulator; VPS33B-interacting protein in polarity and apical restriction; VPS33B-interacting protein involved in polarity and apical protein restriction
Description (eCommerce)
VPS33B-interacting protein (VIPAR) plays a role in lysosomal trafficking. VIPAR may play a role in epithelial polarization through stabilization of apical membrane protein content, possibly via the RAB11A-dependent apical recycling pathway. VIPAR is also involved in direct or indirect transcriptional regulation of E-cadherin. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9H9C1].
Description (Vector)
VIPAS39 encodes a protein involved in the sorting of lysosomal proteins. Mutations in this gene are associated with ARCS2 (arthrogryposis, renal dysfunction, and cholestasis-2). Alternative splicing results in multiple transcript variants.
Gene ID
63894
Gene Name (eCommerce)
VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
Gene Name (Vector)
VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
Gene Symbol
VIPAS39
HGNC ID
HGNC:20347
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1482
ORF Size (bp)
1482 bp
Protein Name (eCommerce)
Spermatogenesis-defective protein 39 homolog
RefSeq ID
NM_022067
RefSeq Synonyms
NM_022067, NM_001193317, NM_001193316, NM_001193315, NM_001193314, BC015054,
Research Areas
Lysosomal Transport,Spermatogenesis,Transcription Factor/Regulator,Transport
Research Areas (Faceted)
cell_biology,developmental_biology,transcription_translation
Species
human
Target Sentence
VPS33B-interacting protein (VIPAR) plays a role in lysosomal trafficking. VIPAR may play a role in epithelial polarization through stabilization of apical membrane protein content, possibly via the RAB11A-dependent apical recycling pathway. VIPAR is also involved in direct or indirect transcriptional regulation of E-cadherin. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9H9C1].
UniGene ID
Hs.16157
UniProt ID (eCommerce)
Q9H9C1

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.