mouse DDR1 Adenovirus
This is an Adenovirus expressing Mouse Ddr1.
ADV-256910
Ad-m-DDR1
Ready-to-use Adenovirus expressing Mouse Ddr1 (discoidin domain receptor family, member 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
6030432F18; AI323681; Cak; CD167a; Nep; PTK3A
Description (Vector)
Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing (By similarity). Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11.
Gene ID
12305
Gene Name (Vector)
discoidin domain receptor family, member 1
Gene Symbol
Ddr1
ORF Size (aa)
2061
ORF Size (bp)
2061 bp
RefSeq ID
NM_007584
RefSeq Synonyms
NM_172962, NM_007584, NM_001198833, NM_001198831, BC065998,
Species
mouse
UniGene ID
Mm.5021
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.