mouse CTH Adenovirus
This is an Adenovirus expressing Mouse Cth.
ADV-256305
Ad-m-CTH
Ready-to-use Adenovirus expressing Mouse Cth (cystathionase (cystathionine gamma-lyase)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
0610010I13Rik; AI314617; BC019483; CSE; Cys3
Description (Vector)
Catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure. Acts as a cysteine-protein sulfhydrase by mediating sulfhydration of target proteins: sulfhydration consists of converting -SH groups into -SSH on specific cysteine residues of target proteins such as GAPDH, PTPN1 and NF-kappa-B subunit RELA, thereby regulating their function.
Gene ID
107869
Gene Name (Vector)
cystathionase (cystathionine gamma-lyase)
Gene Symbol
Cth
ORF Size (aa)
1197
ORF Size (bp)
1197 bp
RefSeq ID
NM_145953
RefSeq Synonyms
NM_145953, BC019483,
Species
mouse
UniGene ID
Mm.28301
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.