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human BMX Over-expression AAV

Name 
AAV-h-BMX
Cat No 
AAV-202208
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human BMX.

AAV-202208
AAV-h-BMX

Ready-to-use AAV expressing Human BMX (BMX non-receptor tyrosine kinase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ETK; PSCTK2; PSCTK3
Description (Vector)
BMX encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Gene ID
660
Gene Name (Vector)
BMX non-receptor tyrosine kinase
Gene Symbol
BMX
HGNC ID
HGNC:1079
ORF Size (aa)
2028
ORF Size (bp)
2028 bp
RefSeq ID
NM_001721
RefSeq Synonyms
NM_203281, NM_001721, NM_001320866, BC016652,
Species
human
UniGene ID
Hs.495731

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.