human BMX shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human BMX.
shADV-202208
Ad-h-BMX-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human BMX (BMX non-receptor tyrosine kinase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ETK; PSCTK2; PSCTK3
Description (Vector)
BMX encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Gene ID
660
Gene Name (Vector)
BMX non-receptor tyrosine kinase
Gene Symbol
BMX
HGNC ID
HGNC:1079
ORF Size (aa)
2028
ORF Size (bp)
2028 bp
RefSeq ID
NM_001721
RefSeq Synonyms
NM_203281, NM_001721, NM_001320866, BC016652,
Species
human
UniGene ID
Hs.495731
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.