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human BLMH Over-expression AAV

Name 
AAV-h-BLMH
Cat No 
AAV-202165
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human BLMH.

AAV-202165
AAV-h-BLMH

Ready-to-use AAV expressing Human BLMH (bleomycin hydrolase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BH; BMH
Description (Vector)
Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily.
Gene ID
642
Gene Name (Vector)
bleomycin hydrolase
Gene Symbol
BLMH
HGNC ID
HGNC:1059
ORF Size (aa)
1368
ORF Size (bp)
1368 bp
RefSeq ID
NM_000386
RefSeq Synonyms
NM_000386, BC003616,
Species
human
UniGene ID
Hs.371914

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.