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human BAAT Over-expression AAV

Name 
AAV-h-BAAT
Cat No 
AAV-201927
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human BAAT.

AAV-201927
AAV-h-BAAT

Ready-to-use AAV expressing Human BAAT (bile acid-CoA:amino acid N-acyltransferase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BACAT; BAT
Description (Vector)
BAAT is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). Two transcript variants encoding the same protein have been found for this gene.
Gene ID
570
Gene Name (Vector)
bile acid-CoA:amino acid N-acyltransferase
Gene Symbol
BAAT
HGNC ID
HGNC:932
ORF Size (aa)
1257
ORF Size (bp)
1257 bp
RefSeq ID
NM_001701
RefSeq Synonyms
NM_001701, NM_001127610, BC107424, BC009567,
Species
human
UniGene ID
Hs.715720

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.