human BAAT shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human BAAT.
shAAV-201927
AAV-h-BAAT-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human BAAT (bile acid-CoA:amino acid N-acyltransferase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BACAT; BAT
Description (Vector)
BAAT is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). Two transcript variants encoding the same protein have been found for this gene.
Gene ID
570
Gene Name (Vector)
bile acid-CoA:amino acid N-acyltransferase
Gene Symbol
BAAT
HGNC ID
HGNC:932
ORF Size (aa)
1257
ORF Size (bp)
1257 bp
RefSeq ID
NM_001701
RefSeq Synonyms
NM_001701, NM_001127610, BC107424, BC009567,
Species
human
UniGene ID
Hs.715720
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.