human CACNB4 Adenovirus
This is an Adenovirus expressing Human MYBL1.
ADV-231518
Ad-h-CACNB4
Ready-to-use Adenovirus expressing Human CACNB4 (calcium voltage-gated channel auxiliary subunit beta 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CAB4; CACNLB4; EA5; EIG9; EJM; EJM4; EJM6
Description (Vector)
CACNB4 encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME). Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
785
Gene Name (Vector)
calcium voltage-gated channel auxiliary subunit beta 4
Gene Symbol
CACNB4
HGNC ID
HGNC:1404
ORF Size (aa)
1563
ORF Size (bp)
1563 bp
RefSeq ID
NM_000726
RefSeq Synonyms
NM_001330118, NM_001330117, NM_001330116, NM_001330115, NM_001330114, NM_001330113, NM_001320722, NM_001145798, NM_001005747, NM_001005746, NM_000726, BC075049,
Species
human
UniGene ID
Hs.120725
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.