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human RNF139 Adenovirus

Name 
Ad-h-RNF139
Cat No 
ADV-230802
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human RNF139.

ADV-230802
Ad-h-RNF139

Ready-to-use Adenovirus expressing Human RNF139 (ring finger protein 139). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
HRCA1; RCA1; TRC8
Description (Vector)
RNF139 is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.
Gene ID
11236
Gene Name (Vector)
ring finger protein 139
Gene Symbol
RNF139
HGNC ID
HGNC:17023
ORF Size (aa)
1995
ORF Size (bp)
1995 bp
RefSeq ID
NM_007218
RefSeq Synonyms
NM_007218, BC064636, BC021571,
Species
human
UniGene ID
Hs.492751

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.