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human APH1B Adenovirus

Name 
Ad-h-APH1B
Cat No 
ADV-230040
Availability
4-5 weeks

This is an Adenovirus expressing Human APH1B.

ADV-230040
Ad-h-APH1B

Ready-to-use Adenovirus expressing Human APH1B (aph-1 homolog B, gamma-secretase subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
APH-1B; PRO1328; PSFL; TAAV688
Description (Vector)
APH1B encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein.
Gene ID
83464
Gene Name (Vector)
aph-1 homolog B, gamma-secretase subunit
Gene Symbol
APH1B
HGNC ID
HGNC:24080
ORF Size (aa)
774
ORF Size (bp)
774 bp
RefSeq ID
NM_031301
RefSeq Synonyms
NM_031301, NM_001145646, BC020905,
Species
human
UniGene ID
Hs.511703

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.