human KANK2 shRNA silencing AAV

Name
AAV-h-KANK2-shRNA

Cat No
shAAV-212618

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human KANK2.

shAAV-212618

AAV-h-KANK2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human KANK2 (KN motif and ankyrin repeat domains 2). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ANKRD25; ankyrin repeat domain-containing protein 25; kidney ankyrin repeat-containing protein 2; KN motif and ankyrin repeat domain-containing protein 2; matrix-remodeling-associated protein 3; MXRA3; NPHS16; PPKWH; SIP; SRC-1-interacting protein; SRC1-interacting protein; SRC-interacting protein

Description (eCommerce)

KANK2/SIP was first identified during a genome wide-screen for proteins that interact with the SRC transcriptional coactivator. KANK2/SIP was also identified by domain and phylogenetic analysis to be a member of the KANK ankyrin-repeat domain-containing protein family. KANK related proteins possess a conserved ankyrin-repeat and coiled-coil domain. KANK2, as well as other KANK proteins, appear to play a role in the formation of actin stress fibers.

Gene ID

25959

Gene Name (eCommerce)

KN motif and ankyrin repeat domains 2

Gene Name (Vector)

KN motif and ankyrin repeat domains 2

Gene Symbol

KANK2

HGNC ID

HGNC:29300

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

2556

ORF Size (bp)

2556 bp

Protein Name (eCommerce)

KN motif and ankyrin repeat domain-containing protein 2

RefSeq ID

NM_015493

RefSeq Synonyms

NM_015493, NM_001329451, NM_001136191, BC098312, BC098286, BC098105, BC082762,

Research Areas

Apoptosis,Cell Cycle,Cytoskeleton,Mitochondrion,Transcription Factor/Regulator

Research Areas (Faceted)

cell_biology,cell_cycle,genetics,transcription_translation

Species

human

Target Sentence

KANK2/SIP was first identified during a genome wide-screen for proteins that interact with the SRC transcriptional coactivator. KANK2/SIP was also identified by domain and phylogenetic analysis to be a member of the KANK ankyrin-repeat domain-containing protein family. KANK related proteins possess a conserved ankyrin-repeat and coiled-coil domain. KANK2, as well as other KANK proteins, appear to play a role in the formation of actin stress fibers.

UniGene ID

Hs.284208

UniProt ID (eCommerce)

Q63ZY3

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.