human ATP6V0D1 Over-expression AAV
This is an AAV expressing Human ATP6V0D1.
AAV-201752
AAV-h-ATP6V0D1
Ready-to-use AAV expressing Human ATP6V0D1 (ATPase H+ transporting V0 subunit d1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ATP6D; ATP6DV; P39; VATX; VMA6; VPATPD
Description (Vector)
ATP6V0D1 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is known as the D subunit and is found ubiquitously.
Gene ID
9114
Gene Name (Vector)
ATPase H+ transporting V0 subunit d1
Gene Symbol
ATP6V0D1
HGNC ID
HGNC:13724
ORF Size (aa)
1056
ORF Size (bp)
1056 bp
RefSeq ID
NM_004691
RefSeq Synonyms
NM_004691, BC008861,
Species
human
UniGene ID
Hs.106876
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.