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human RBM14 Adenovirus

Name 
Ad-h-RBM14
Cat No 
ADV-229725
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human RBM14.

ADV-229725
Ad-h-RBM14

Ready-to-use Adenovirus expressing Human RBM14 (RNA binding motif protein 14). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
COAA; paraspeckle protein 2; PSP2; RNA-binding motif protein 14; RNA-binding protein 14; RRM-containing coactivator activator/modulator; SIP; synaptotagmin-interacting protein; SYT-interacting protein; SYTIP1; TMEM137; transmembrane protein 137
Description (eCommerce)
CoAA (coactivator activator) is also known as RBM14 (RNA binding motif protein 14) because of the presence of two RNA recognition motifs (RRMs) in its N-terminus. CoAA has been observed to mediate the coupled processes of transcription and splicing in a promoter-specific manner.
Description (Vector)
RBM14 encodes a ribonucleoprotein that functions as a general nuclear coactivator, and an RNA splicing modulator. This protein contains two RNA recognition motifs (RRM) at the N-terminus, and multiple hexapeptide repeat domain at the C-terminus that interacts with thyroid hormone receptor-binding protein (TRBP), and is required for transcription activation. Alternatively spliced transcript variants encoding different isoforms (with opposing effects on transcription) have been described for this gene.
Gene ID
10432
Gene Name (eCommerce)
RNA binding motif protein 14
Gene Name (Vector)
RNA binding motif protein 14
Gene Symbol
RBM14
HGNC ID
HGNC:14219
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2010
ORF Size (bp)
2010 bp
Protein Name (eCommerce)
RNA-binding protein 14
RefSeq ID
NM_006328
RefSeq Synonyms
NM_006328, NM_001198837, NM_001198836, BC000488,
Research Areas
DNA Damage/Repair,DNA Replication,Estrogen Signaling,Histone Modification,Nuclear Receptor Coactivators,RNA Binding,Signal Transduction,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,genetics,transcription_translation,signal_transduction
Species
human
Target Sentence
CoAA (coactivator activator) is also known as RBM14 (RNA binding motif protein 14) because of the presence of two RNA recognition motifs (RRMs) in its N-terminus. CoAA has been observed to mediate the coupled processes of transcription and splicing in a promoter-specific manner.
UniGene ID
Hs.
UniProt ID (eCommerce)
Q96PK6

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.