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human MSH3 Adenovirus

Name 
Ad-h-MSH3
Cat No 
ADV-229312
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human MSH3.

ADV-229312
Ad-h-MSH3

Ready-to-use Adenovirus expressing Human MSH3 (mutS homolog 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
divergent upstream protein; DNA mismatch repair protein Msh3; DUP; epididymis secretory sperm binding protein; FAP4; hMSH3; mismatch repair protein 1; MRP1
Description (eCommerce)
MSH3 forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer [taken from NCBI Entrez Gene (Gene ID: 4437)].
Description (Vector)
MSH3 forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer.
Gene ID
4437
Gene Name (eCommerce)
mutS homolog 3
Gene Name (Vector)
mutS homolog 3
Gene Symbol
MSH3
HGNC ID
HGNC:7326
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3414
ORF Size (bp)
3414 bp
Protein Name (eCommerce)
DNA mismatch repair protein Msh3
RefSeq ID
NM_002439
RefSeq Synonyms
NM_002439, BC130436, BC130434,
Research Areas
Cancer,Colorectal Cancer,DNA Damage/Repair,Helicase Activity,Immunology
Research Areas (Faceted)
cancer,genetics,transcription_translation,cell_biology,immunology
Species
human
Target Sentence
MSH3 forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer [taken from NCBI Entrez Gene (Gene ID: 4437)].
UniGene ID
Hs.280987
UniProt ID (eCommerce)
P20585

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.