human WISP3 Adenovirus
This is an Adenovirus expressing Human WISP3.
ADV-227804
Ad-h-WISP3
Ready-to-use Adenovirus expressing Human WISP3 (WNT1 inducible signaling pathway protein 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CCN6; LIBC; PPAC; PPD; WISP-3
Description (Vector)
WISP3 encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. WISP3 is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of this gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
8838
Gene Name (Vector)
WNT1 inducible signaling pathway protein 3
Gene Symbol
WISP3
HGNC ID
HGNC:12771
ORF Size (aa)
714
RefSeq ID
NM_003880
RefSeq Synonyms
NM_198239, NM_003880, BC105941, BC105940, BC012028,
Species
human
UniGene ID
Hs.558428
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.