human ARNTL2 Over-expression AAV

Name 
AAV-h-ARNTL2
Cat No 
AAV-201456
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ARNTL2.

AAV-201456
AAV-h-ARNTL2

Ready-to-use AAV expressing Human ARNTL2 (aryl hydrocarbon receptor nuclear translocator like 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bHLHe6; BMAL2; CLIF; MOP9; PASD9
Description (Vector)
ARNTL2 encodes a basic helix-loop-helix transcription factor belonging to the PAS (PER, ARNT, SIM) superfamily. The PAS proteins play important roles in adaptation to low atmospheric and cellular oxygen levels, exposure to certain environmental pollutants, and diurnal oscillations in light and temperature. This protein forms a transcriptionally active heterodimer with the circadian CLOCK protein, the structurally related MOP4, and hypoxia-inducible factors, such as HIF1alpha. Consistent with its role as a biologically relevant partner of circadian and hypoxia factors, this protein is coexpressed in regions of the brain such as the thalamus, hypothalamus, and amygdala. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gene ID
56938
Gene Name (Vector)
aryl hydrocarbon receptor nuclear translocator like 2
Gene Symbol
ARNTL2
HGNC ID
HGNC:18984
ORF Size (aa)
1800
ORF Size (bp)
1800 bp
RefSeq ID
NM_020183
RefSeq Synonyms
NM_020183, NM_001248005, NM_001248004, NM_001248003, NM_001248002, BC125062, BC125061,
Species
human
UniGene ID
Hs.663740

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.