human TRIP11 Adenovirus
This is an Adenovirus expressing Human TRIP11.
ADV-226496
Ad-h-TRIP11
Ready-to-use Adenovirus expressing Human TRIP11 (thyroid hormone receptor interactor 11). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ACG1A; CEV14; clonal evolution-related gene on chromosome 14 protein; GMAP210; GMAP-210; golgi-associated microtubule-binding protein 210; Golgi-microtubule-associated protein of 210 kDa; thyroid receptor-interacting protein 11; TR-interacting protein 11; TRIP-11; TRIP230
Description (eCommerce)
TRIP11/TRIP230 was identified as a co-activator of the thyroid hormone receptor (TR). TRIP230 has also been identified as an essential coactivator of AHR (aryl-hydrocarbon receptor) and HIF (hypoxia inducible factor). Additionally, TRIP11/TRIP230 has been observed to play a role in maintaining cis-Golgi structure.
Description (Vector)
TRIP11 was identified based on the interaction of its protein product with thyroid hormone receptor beta. This protein is associated with the Golgi apparatus. The N-terminal region of the protein binds Golgi membranes and the C-terminal region binds the minus ends of microtubules; thus, the protein is thought to play a role in assembly and maintenance of the Golgi ribbon structure around the centrosome. Mutations in this gene cause achondrogenesis type IA.
Gene ID
9321
Gene Name (eCommerce)
thyroid hormone receptor interactor 11
Gene Name (Vector)
thyroid hormone receptor interactor 11
Gene Symbol
TRIP11
HGNC ID
HGNC:12305
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
5940
ORF Size (bp)
5940 bp
Protein Name (eCommerce)
Thyroid receptor-interacting protein 11
RefSeq ID
NM_004239
RefSeq Synonyms
NM_004239, NM_001321851, BC146845, BC002656,
Research Areas
Cytoskeleton,Golgi Apparatus,Nuclear Receptor Coactivators,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
TRIP11/TRIP230 was identified as a co-activator of the thyroid hormone receptor (TR). TRIP230 has also been identified as an essential coactivator of AHR (aryl-hydrocarbon receptor) and HIF (hypoxia inducible factor). Additionally, TRIP11/TRIP230 has been observed to play a role in maintaining cis-Golgi structure.
UniGene ID
Hs.632339
UniProt ID (eCommerce)
Q15643
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.