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human TPX2 Adenovirus

Name 
Ad-h-TPX2
Cat No 
ADV-226311
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human TPX2.

ADV-226311
Ad-h-TPX2

Ready-to-use Adenovirus expressing Human TPX2 (TPX2, microtubule nucleation factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
C20orf1; C20orf2; differentially expressed in cancerous and non-cancerous lung cells 2; differentially expressed in lung cells; DIL2; DIL-2; FLS353; GD:C20orf1; HCA519; HCTP4; hepatocellular carcinoma-associated antigen 519; hepatocellular carcinoma-associated antigen 90; p100; preferentially expressed in colorectal cancer; protein fls353; REPP86; restricted expression proliferation associated protein 100; Restricted expression proliferation-associated protein 100; targeting protein for Xklp2; TPX2, microtubule-associated protein homolog; TPX2, microtubule-associated, homolog
Description (eCommerce)
TPX2 is a microtubule associated protein (MAP) that co-localizes with spindle microtubules during M-phase of the cell cycle. It may function to nucleate microtubules and initiate microtubule polymerization and assembly for spindle formation. TPX2 is a target of RanGTP, a small GTPase that coordinates spindle assembly. TPX2 protein levels peak during mitosis and are tightly regulated by ubiquitination during the cell cycle.
Gene ID
22974
Gene Name (eCommerce)
TPX2, microtubule nucleation factor
Gene Name (Vector)
TPX2, microtubule nucleation factor
Gene Symbol
TPX2
HGNC ID
HGNC:1249
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2244
ORF Size (bp)
2244 bp
Protein Name (eCommerce)
Targeting protein for Xklp2
RefSeq ID
NM_012112
RefSeq Synonyms
NM_012112, BC020207, BC004136,
Research Areas
Apoptosis,Cancer,Cell Cycle,Cell Division,Cytoskeleton,PLK1 Signaling,Signal Transduction
Research Areas (Faceted)
cancer,cell_biology,cell_cycle,genetics,signal_transduction
Species
human
Target Sentence
TPX2 is a microtubule associated protein (MAP) that co-localizes with spindle microtubules during M-phase of the cell cycle. It may function to nucleate microtubules and initiate microtubule polymerization and assembly for spindle formation. TPX2 is a target of RanGTP, a small GTPase that coordinates spindle assembly. TPX2 protein levels peak during mitosis and are tightly regulated by ubiquitination during the cell cycle.
UniGene ID
Hs.244580
UniProt ID (eCommerce)
Q9ULW0

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.