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human TOX Adenovirus

Name 
Ad-h-TOX
Cat No 
ADV-226224
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human TOX.

ADV-226224
Ad-h-TOX

Ready-to-use Adenovirus expressing Human TOX (thymocyte selection associated high mobility group box). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
thymocyte selection-associated high mobility group box protein TOX; thymus high mobility group box protein TOX; TOX1
Description (eCommerce)
The thymocyte selection-associated high mobility group box protein TOX is a member of the conserved high-motility group (HMG)-box superfamily. HMG boxes are DNA binding domains found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. TOX functions to regulate T-cell development in the thymus. [taken from NCBI Entrez Gene (Gene ID: 9760)].
Description (Vector)
TOX contains a HMG box DNA binding domain. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. This protein may function to regulate T-cell development.
Gene ID
9760
Gene Name (eCommerce)
thymocyte selection associated high mobility group box
Gene Name (Vector)
thymocyte selection associated high mobility group box
Gene Symbol
TOX
HGNC ID
HGNC:18988
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1581
ORF Size (bp)
1581 bp
Protein Name (eCommerce)
Thymocyte selection-associated high mobility group box protein TOX
RefSeq ID
NM_014729
RefSeq Synonyms
NM_014729, BC016665,
Research Areas
Chromatin Remodeling
Research Areas (Faceted)
cell_biology,genetics
Species
human
Target Sentence
The thymocyte selection-associated high mobility group box protein TOX is a member of the conserved high-motility group (HMG)-box superfamily. HMG boxes are DNA binding domains found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. TOX functions to regulate T-cell development in the thymus. [taken from NCBI Entrez Gene (Gene ID: 9760)].
UniGene ID
Hs.634856
UniProt ID (eCommerce)
O94900

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.