human TNFRSF1B Adenovirus
This is an Adenovirus expressing Human TNFRSF1B.
ADV-226086
Ad-h-TNFRSF1B
Ready-to-use Adenovirus expressing Human TNFRSF1B (TNF receptor superfamily member 1B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD120b; p75; p75TNFR; TBPII; TNF-R-II; TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80
Description (Vector)
TNFRSF1B is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
Gene ID
7133
Gene Name (Vector)
TNF receptor superfamily member 1B
Gene Symbol
TNFRSF1B
HGNC ID
HGNC:11917
ORF Size (aa)
1386
ORF Size (bp)
1386 bp
RefSeq ID
NM_001066
RefSeq Synonyms
NM_001066, BC052977,
Species
human
UniGene ID
Hs.256278
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.