mouse TNFRSF1B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Tnfrsf1b.
shAAV-274707
AAV-m-TNFRSF1B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Tnfrsf1b (tumor necrosis factor receptor superfamily, member 1b). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD120b; p75; TNF-alphaR2; TNF-R-II; TNF-R2; TNF-R75; TNFalpha-R2; TNFBR; Tnfr-1; Tnfr2; TNFR80; TNFRII
Description (Vector)
Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
Gene ID
21938
Gene Name (Vector)
tumor necrosis factor receptor superfamily, member 1b
Gene Symbol
Tnfrsf1b
ORF Size (aa)
1425
ORF Size (bp)
1425 bp
RefSeq ID
NM_011610
RefSeq Synonyms
NM_011610, BC141405,
Species
mouse
UniGene ID
Mm.235328
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.