human T Adenovirus

Name 
Ad-h-T
Cat No 
ADV-224874
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human T.

ADV-224874
Ad-h-T

Ready-to-use Adenovirus expressing Human T (T brachyury transcription factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
brachyury protein; protein T; SAVA; T; T brachyury transcription factor; T, brachyury homolog; T-box transcription factor T; TFT
Description (eCommerce)
TBXT is involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic site (called T site) and activates gene transcription when bound to such a site. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O15178].
Description (Vector)
T is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
6862
Gene Name (eCommerce)
T-box transcription factor T
Gene Name (Vector)
T brachyury transcription factor
Gene Symbol
T
HGNC ID
HGNC:11515
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1134
Protein Name (eCommerce)
Brachyury protein
RefSeq ID
NM_003181
RefSeq Synonyms
NM_003181, NM_001270484, BC098425,
Research Areas
Neurodevelopment,RNA Binding,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,developmental_biology,neurobiology,transcription_translation
Species
human
Target Sentence
TBXT is involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic site (called T site) and activates gene transcription when bound to such a site. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O15178].
UniGene ID
Hs.389457
UniProt ID (eCommerce)
O15178

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.