human APLN Over-expression AAV

Name
AAV-h-APLN

Cat No
AAV-201156

Availability
4-5 weeks

Categories
AAV, Over-Expression

This is an AAV expressing Human APLN.

AAV-201156

AAV-h-APLN

Ready-to-use AAV expressing Human APLN (apelin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

APEL; XNPEP2

Description (Vector)

APLN encodes a peptide that functions as an endogenous ligand for the G protein coupled receptor APJ. The encoded protein is synthesized as a prepropeptide that is processed into biologically active C-terminal fragments. The peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1.

Gene ID

8862

Gene Name (Vector)

apelin

Gene Symbol

APLN

HGNC ID

HGNC:16665

ORF Size (aa)

234

ORF Size (bp)

234 bp

RefSeq ID

NM_017413

RefSeq Synonyms

NM_017413, BC021104,

Species

human

UniGene ID

Hs.303084

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.