Promotional banner reading 'FALL SAVINGS' with expiry date August 31 on an orange background; features a group of people with orange stacked blocks on the right and discounts for services and catalog products.

human SMARCA1 Adenovirus

Name 
Ad-h-SMARCA1
Cat No 
ADV-223707
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human SMARCA1.

ADV-223707
Ad-h-SMARCA1

Ready-to-use Adenovirus expressing Human SMARCA1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ATP-dependent helicase SMARCA1; global transcription activator homologous sequence; hSNF2L; ISWI; nucleosome-remodeling factor subunit SNF2L; NURF140; probable global transcription activator SNF2L1; SNF2L; SNF2L1; SNF2LB; SNF2-like 1; SNF2LT; sucrose nonfermenting 2-like protein 1; SWI; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1; SWI2
Description (eCommerce)
The SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin (SMARC), also called BRG1-associated factors (BAFs), have been identified as components of the human SWI/SNF-like chromatin-remodeling protein complexes. Member of this family have helicase and ATPase activities that alter chromatin structure to facilitate gene transcription. SMARCA1/SNF2L is a component of the human NURF (nucleosome remodeling factor) involved in the regulation of genes involved in neuronal development. SMARCA1/SNF2L is also a component of the heterodimeric complex CERF [CECR2(cat eye syndrome chromosome region, candidate 2)-containing remodeling factor].
Description (Vector)
SMARCA1 encodes a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
6594
Gene Name (eCommerce)
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
Gene Name (Vector)
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
Gene Symbol
SMARCA1
HGNC ID
HGNC:11097
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3213
ORF Size (bp)
3213 bp
Protein Name (eCommerce)
Probable global transcription activator SNF2L1
RefSeq ID
NM_003069
RefSeq Synonyms
NM_139035, NM_003069, NM_001282875, NM_001282874, BC143954, BC117447,
Research Areas
Brain Development,Chromatin Remodeling,Helicase Activity,Neurobiology,Neurodevelopment,Transcription Factor/Regulator
Research Areas (Faceted)
neurobiology,developmental_biology,cell_biology,transcription_translation,genetics
Species
human
Target Sentence
The SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin (SMARC), also called BRG1-associated factors (BAFs), have been identified as components of the human SWI/SNF-like chromatin-remodeling protein complexes. Member of this family have helicase and ATPase activities that alter chromatin structure to facilitate gene transcription. SMARCA1/SNF2L is a component of the human NURF (nucleosome remodeling factor) involved in the regulation of genes involved in neuronal development. SMARCA1/SNF2L is also a component of the heterodimeric complex CERF [CECR2(cat eye syndrome chromosome region, candidate 2)-containing remodeling factor].
UniGene ID
Hs.152292
UniProt ID (eCommerce)
P28370

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.