human SFRS2IP Adenovirus

Name 
Ad-h-SFRS2IP
Cat No 
ADV-222805
Availability
4-5 weeks

This is an Adenovirus expressing Human IMPACT.

ADV-222805
Ad-h-SFRS2IP

Ready-to-use Adenovirus expressing Human SCAF11 (SR-related CTD associated factor 11). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CASP11; CTD-associated SR protein 11; protein SCAF11; renal carcinoma antigen NY-REN-40; SC35-interacting protein 1; serine/arginine-rich splicing factor 2-interacting protein; SFRS2-interacting protein; SFRS2IP; SIP1; splicing factor, arginine/serine-rich 2-interacting protein; splicing regulatory protein 129; SR-related and CTD-associated factor 11; SRRP129; SRSF2-interacting protein; SRSF2IP
Description (eCommerce)
SFRS2IP was identified as factor that interacts with SC35, an SR family member critical to mRNA splicing. SFRS2IP contains an arginine-serine-rich (RS) domain and lacks any known RNA-binding motifs. SFRS2IP may have an important role in splicesome assembly since it has been demonstrated to interact with several proteins involved in the early steps of splicesome assembly and the finding that splicesomal complexes A and B are not formed in SFRS2IP depleted extracts.
Gene ID
9169
Gene Name (eCommerce)
SR-related CTD associated factor 11
Gene Name (Vector)
SR-related CTD associated factor 11
Gene Symbol
SCAF11
HGNC ID
HGNC:10784
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
4389
ORF Size (bp)
4389 bp
Protein Name (eCommerce)
Protein SCAF11
RefSeq ID
NM_004719
RefSeq Synonyms
NM_004719, BC141552,
Research Areas
Gene Expression,mRNA Processing,mRNA Splicing,RNA Processing,Spliceosome,Zinc-finger
Research Areas (Faceted)
genetics,transcription_translation,cell_biology
Species
human
Target Sentence
SFRS2IP was identified as factor that interacts with SC35, an SR family member critical to mRNA splicing. SFRS2IP contains an arginine-serine-rich (RS) domain and lacks any known RNA-binding motifs. SFRS2IP may have an important role in splicesome assembly since it has been demonstrated to interact with several proteins involved in the early steps of splicesome assembly and the finding that splicesomal complexes A and B are not formed in SFRS2IP depleted extracts.
UniGene ID
Hs.715491
UniProt ID (eCommerce)
Q99590

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.