human RNASEH2B Adenovirus

Name 
Ad-h-RNASEH2B
Cat No 
ADV-221307
Availability
4-5 weeks

This is an Adenovirus expressing Human RNASEH2B.

ADV-221307
Ad-h-RNASEH2B

Ready-to-use Adenovirus expressing Human RNASEH2B (ribonuclease H2 subunit B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AGS2; DLEU8
Description (Vector)
RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2).
Gene ID
79621
Gene Name (Vector)
ribonuclease H2 subunit B
Gene Symbol
RNASEH2B
HGNC ID
HGNC:25671
ORF Size (aa)
996
RefSeq ID
NM_024570
RefSeq Synonyms
NM_024570, NM_001142279, BC036744,
Species
human
UniGene ID
Hs.306291

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.