human PURB Adenovirus

Name 
Ad-h-PURB
Cat No 
ADV-220397
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human PURB.

ADV-220397
Ad-h-PURB

Ready-to-use Adenovirus expressing Human PURB (purine rich element binding protein B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
PURBETA; Purine-rich element-binding protein B; transcriptional activator protein Pur-beta
Description (eCommerce)
Pur-beta (purine-rich element binding protein B) is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of the Pur-beta gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia [taken from NCBI Entrez Gene (Gene ID: 5814)].
Description (Vector)
PURB product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.
Gene ID
5814
Gene Name (eCommerce)
purine rich element binding protein B
Gene Name (Vector)
purine rich element binding protein B
Gene Symbol
PURB
HGNC ID
HGNC:9702
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
939
Protein Name (eCommerce)
Transcriptional activator protein Pur-beta
RefSeq ID
NM_033224
RefSeq Synonyms
NM_033224, BC101737, BC101735,
Research Areas
Cell Cycle,DNA Replication,mRNA Binding,Replication,Transcription Factor/Regulator,Translational Control
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
Pur-beta (purine-rich element binding protein B) is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of the Pur-beta gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia [taken from NCBI Entrez Gene (Gene ID: 5814)].
UniGene ID
Hs.596321
UniProt ID (eCommerce)
Q96QR8

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.