human ALDH5A1 Over-expression AAV

Name 
AAV-h-ALDH5A1
Cat No 
AAV-200743
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ALDH5A1.

AAV-200743
AAV-h-ALDH5A1

Ready-to-use AAV expressing Human ALDH5A1 (aldehyde dehydrogenase 5 family member A1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
SSADH; SSDH
Description (Vector)
This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.
Gene ID
7915
Gene Name (Vector)
aldehyde dehydrogenase 5 family member A1
Gene Symbol
ALDH5A1
HGNC ID
HGNC:408
ORF Size (aa)
1608
ORF Size (bp)
1608 bp
RefSeq ID
NM_170740
RefSeq Synonyms
NM_170740, NM_001080, BC034321,
Species
human
UniGene ID
Hs.371723

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.