human PPHLN1 Adenovirus

Name
Ad-h-PPHLN1

Cat No
ADV-219534

Availability
4-5 weeks

This is an Adenovirus expressing Human PPHLN1.

ADV-219534

Ad-h-PPHLN1

Ready-to-use Adenovirus expressing Human PPHLN1 (periphilin 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

CR; HSPC206; HSPC232

Description (Vector)

PPHLN1 is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis. This protein interacts with periplakin, which is known as a precursor of the cornified cell envelope. The cellular localization pattern and insolubility of this protein suggest that it may play a role in epithelial differentiation and contribute to epidermal integrity and barrier formation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Gene ID

51535

Gene Name (Vector)

periphilin 1

Gene Symbol

PPHLN1

HGNC ID

HGNC:19369

ORF Size (aa)

777

RefSeq ID

NM_016488

RefSeq Synonyms

NM_201515, NM_201440, NM_201439, NM_201438, NM_016488, NM_001143789, NM_001143788, NM_001143787, BC039832,

Species

human

UniGene ID

Hs.444157

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.