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human PPFIA1 Adenovirus

Name 
Ad-h-PPFIA1
Cat No 
ADV-219524
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human PPFIA1.

ADV-219524
Ad-h-PPFIA1

Ready-to-use Adenovirus expressing Human PPFIA1 (PTPRF interacting protein alpha 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
LAR-interacting protein 1; LIP.1; LIP1; LIP-1; LIPRIN; Liprin-alpha1; liprin-alpha-1; protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1; protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1; PTPRF-interacting protein alpha-1
Description (eCommerce)
Liprin-alpha-1 is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions [taken from NCBI Entrez Gene (Gene ID: 8500)].
Description (Vector)
PPFIA1 is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Gene ID
8500
Gene Name (eCommerce)
PTPRF interacting protein alpha 1
Gene Name (Vector)
PTPRF interacting protein alpha 1
Gene Symbol
PPFIA1
HGNC ID
HGNC:9245
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3609
ORF Size (bp)
3609 bp
Protein Name (eCommerce)
Liprin-alpha-1
RefSeq ID
NM_003626
RefSeq Synonyms
NM_177423, NM_003626, BC034046,
Research Areas
Signal Transduction
Research Areas (Faceted)
signal_transduction
Species
human
Target Sentence
Liprin-alpha-1 is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions [taken from NCBI Entrez Gene (Gene ID: 8500)].
UniGene ID
Hs.530749
UniProt ID (eCommerce)
Q13136

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.