human PLA2G5 Adenovirus

Name
Ad-h-PLA2G5

Cat No
ADV-219078

Availability
4-5 weeks

This is an Adenovirus expressing Human PLA2G5.

ADV-219078

Ad-h-PLA2G5

Ready-to-use Adenovirus expressing Human PLA2G5 (phospholipase A2 group V). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

FRFB; GV-PLA2; hVPLA(2); PLA2-10

Description (Vector)

PLA2G5 is a member of the secretory phospholipase A2 family. It is located in a tightly-linked cluster of secretory phospholipase A2 genes on chromosome 1. The encoded enzyme catalyzes the hydrolysis of membrane phospholipids to generate lysophospholipids and free fatty acids including arachidonic acid. It preferentially hydrolyzes linoleoyl-containing phosphatidylcholine substrates. Secretion of this enzyme is thought to induce inflammatory responses in neighboring cells. Alternatively spliced transcript variants have been found, but their full-length nature has not been determined.

Gene ID

5322

Gene Name (Vector)

phospholipase A2 group V

Gene Symbol

PLA2G5

HGNC ID

HGNC:9038

ORF Size (aa)

417

RefSeq ID

NM_000929

RefSeq Synonyms

NM_000929, BC036792,

Species

human

UniGene ID

Hs.319438

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.