human PFKFB1 Adenovirus
This is an Adenovirus expressing Human PFKFB1.
ADV-218666
Ad-h-PFKFB1
Ready-to-use Adenovirus expressing Human PFKFB1 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
F6PK; HL2K; PFRX
Description (Vector)
PFKFB1 encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.
Gene ID
5207
Gene Name (Vector)
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
Gene Symbol
PFKFB1
HGNC ID
HGNC:8872
ORF Size (aa)
816
RefSeq ID
NM_002625
RefSeq Synonyms
NM_002625, NM_001271805, NM_001271804, BC096079, BC096078, BC096077,
Species
human
UniGene ID
Hs.444304
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.