human PADI3 Adenovirus

Name
Ad-h-PADI3

Cat No
ADV-218115

Availability
4-5 weeks

This is an Adenovirus expressing Human PADI3.

ADV-218115

Ad-h-PADI3

Ready-to-use Adenovirus expressing Human PADI3 (peptidyl arginine deiminase 3). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

PAD3; PDI3

Description (Vector)

PADI3 encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type III enzyme modulates hair structural proteins, such as filaggrin in the hair follicle and trichohyalin in the inner root sheath, during hair follicle formation. Together with the type I enzyme, this enzyme may also play a role in terminal differentiation of the epidermis. PADI3 exists in a cluster with four other paralogous genes.

Gene ID

51702

Gene Name (Vector)

peptidyl arginine deiminase 3

Gene Symbol

PADI3

HGNC ID

HGNC:18337

ORF Size (aa)

1995

ORF Size (bp)

1995 bp

RefSeq ID

NM_016233

RefSeq Synonyms

NM_016233, BC109092, BC109091, BC041592,

Species

human

UniGene ID

Hs.149195

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.