human OXCT1 Adenovirus
This is an Adenovirus expressing Human OXCT1.
ADV-218022
Ad-h-OXCT1
Ready-to-use Adenovirus expressing Human OXCT1 (3-oxoacid CoA-transferase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
3-oxoacid CoA transferase; 3-oxoacid CoA-transferase 1; epididymis secretory sperm binding protein; OXCT; SCOT; SCOT-s; somatic-type succinyl-CoA:3-oxoacid CoA-transferase; succinyl CoA:3-oxoacid CoA transferase; succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial; succinyl-CoA:3-ketoacid-CoA transferase
Description (eCommerce)
OXCT1 is a key enzyme for ketone body catabolism. OXCT1 transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P55809].
Description (Vector)
OXCT1 encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency.
Gene ID
5019
Gene Name (eCommerce)
3-oxoacid CoA-transferase 1
Gene Name (Vector)
3-oxoacid CoA-transferase 1
Gene Symbol
OXCT1
HGNC ID
HGNC:8527
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1563
ORF Size (bp)
1563 bp
Protein Name (eCommerce)
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial
RefSeq ID
NM_000436
RefSeq Synonyms
NM_000436, BC009001,
Research Areas
Metabolism/Metabolic Process,Mitochondrion
Research Areas (Faceted)
cell_biology,metabolism
Species
human
Target Sentence
OXCT1 is a key enzyme for ketone body catabolism. OXCT1 transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P55809].
UniGene ID
Hs.278277
UniProt ID (eCommerce)
P55809
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.