human ORC6L Adenovirus
This is an Adenovirus expressing Human ORC6L.
ADV-217929
Ad-h-ORC6L
Ready-to-use Adenovirus expressing Human ORC6 (origin recognition complex subunit 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ORC6L; origin recognition complex subunit 6
Description (eCommerce)
ORC6 (origin recognition complex, subunit six) is one of six subunits that make up the origin recognition complex (ORC). The ORC serves as a scaffold for proteins involved in the initiation of replication. In addition to playing an important role in DNA replication, ORC6 has also been shown to be important to cytokinesis and to associate with kinetochores during mitosis.
Description (Vector)
The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.
Gene ID
23594
Gene Name (eCommerce)
origin recognition complex subunit 6
Gene Name (Vector)
origin recognition complex subunit 6
Gene Symbol
ORC6
HGNC ID
HGNC:17151
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
759
Protein Name (eCommerce)
Origin recognition complex subunit 6
RefSeq ID
NM_014321
RefSeq Synonyms
NM_014321, BC063565, BC039032,
Research Areas
Cell Cycle,Cell Division,DNA Replication,Replication
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
ORC6 (origin recognition complex, subunit six) is one of six subunits that make up the origin recognition complex (ORC). The ORC serves as a scaffold for proteins involved in the initiation of replication. In addition to playing an important role in DNA replication, ORC6 has also been shown to be important to cytokinesis and to associate with kinetochores during mitosis.
UniGene ID
Hs.49760
UniProt ID (eCommerce)
Q9Y5N6
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.