human OLIG2 Adenovirus

Name
Ad-h-OLIG2

Cat No
ADV-217410

Availability
4-5 weeks

This is an Adenovirus expressing Human OLIG2.

ADV-217410

Ad-h-OLIG2

Ready-to-use Adenovirus expressing Human OLIG2 (oligodendrocyte lineage transcription factor 2). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

BHLHB1; bHLHe19; OLIGO2; PRKCBP2; RACK17

Description (Vector)

OLIG2 encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome.

Gene ID

10215

Gene Name (Vector)

oligodendrocyte lineage transcription factor 2

Gene Symbol

OLIG2

HGNC ID

HGNC:9398

ORF Size (aa)

972

ORF Size (bp)

972 bp

RefSeq ID

NM_005806

RefSeq Synonyms

NM_005806, BC047511, BC036245,

Species

human

UniGene ID

Hs.176977

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.