human NR1H2 Adenovirus
This is an Adenovirus expressing Human NR1H2.
ADV-217031
Ad-h-NR1H2
Ready-to-use Adenovirus expressing Human NR1H2 (nuclear receptor subfamily 1 group H member 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
LXR-b; LXRB; NER; NER-I; RIP15; UNR
Description (Vector)
The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 (PubMed 19436111)).(supplied by OMIM, Jan 2010)
Gene ID
7376
Gene Name (Vector)
nuclear receptor subfamily 1 group H member 2
Gene Symbol
NR1H2
HGNC ID
HGNC:7965
ORF Size (aa)
1386
ORF Size (bp)
1386 bp
RefSeq ID
NM_007121
RefSeq Synonyms
NM_007121, NM_001256647, BC074500, BC047750, BC033500, BC007790,
Species
human
UniGene ID
Hs.432976
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.