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human FGFBP1 shRNA silencing AAV

Name 
AAV-h-FGFBP1-shRNA
Cat No 
shAAV-208986
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human FGFBP1.

shAAV-208986
AAV-h-FGFBP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FGFBP1 (fibroblast growth factor binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
FGF-BP; FGF-BP1; FGFBP; FGFBP-1; HBP17
Description (Vector)
FGFBP1 encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4.
Gene ID
9982
Gene Name (Vector)
fibroblast growth factor binding protein 1
Gene Symbol
FGFBP1
HGNC ID
HGNC:19695
ORF Size (aa)
705
ORF Size (bp)
705 bp
RefSeq ID
NM_005130
RefSeq Synonyms
NM_005130, BC008910, BC003628,
Species
human
UniGene ID
Hs.1690

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.