human MYH9 Adenovirus

Name 
Ad-h-MYH9
Cat No 
ADV-216174
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human MYH9.

ADV-216174
Ad-h-MYH9

Ready-to-use Adenovirus expressing Human MYH9 (myosin heavy chain 9). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BDPLT6; cellular myosin heavy chain, type A; DFNA17; EPSTS; FTNS; MATINS; MHA; Myosin heavy chain 9; Myosin heavy chain, non-muscle IIa; myosin, heavy chain 9, non-muscle; myosin-9; NMHC-II-A; NMMHC II-a; NMMHCA; NMMHC-A; NMMHC-IIA; non-muscle myosin heavy chain 9; non-muscle myosin heavy chain A; non-muscle myosin heavy chain IIa; nonmuscle myosin heavy chain II-A; non-muscle myosin heavy polypeptide 9
Description (eCommerce)
Mysosin-9 (MYH9) is a cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. During cell spreading, mysosin 9 plays an important role in cytoskeleton reorganization, focal contacts formation (in the margins but not the central part of spreading cells), and lamellipodial retraction; this function is mechanically antagonized by MYH10 [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P35579].
Description (Vector)
MYH9 encodes a conventional non-muscle myosin; this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness.
Gene ID
4627
Gene Name (eCommerce)
myosin heavy chain 9
Gene Name (Vector)
myosin heavy chain 9
Gene Symbol
MYH9
HGNC ID
HGNC:7579
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
5883
ORF Size (bp)
5883 bp
Protein Name (eCommerce)
Myosin-9
RefSeq ID
NM_002473
RefSeq Synonyms
NM_002473, BC150170, BC150169, BC011915,
Research Areas
Angiogenesis,Axon Guidance,Cardiology,Cardiovascular,Cell Cycle,Cytoskeleton,EGFR Signaling,Host-Virus Interactions,Immunology,Neurobiology,Signal Transduction
Research Areas (Faceted)
cancer,cardiovascular,cell_biology,cell_cycle,developmental_biology,genetics,immunology,infectious_disease,neurobiology,signal_transduction
Species
human
Target Sentence
Mysosin-9 (MYH9) is a cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. During cell spreading, mysosin 9 plays an important role in cytoskeleton reorganization, focal contacts formation (in the margins but not the central part of spreading cells), and lamellipodial retraction; this function is mechanically antagonized by MYH10 [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P35579].
UniGene ID
Hs.474751
UniProt ID (eCommerce)
P35579

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.