human MYH10 Adenovirus

Name 
Ad-h-MYH10
Cat No 
ADV-216155
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human MYH10.

ADV-216155
Ad-h-MYH10

Ready-to-use Adenovirus expressing Human MYH10 (myosin heavy chain 10). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
cellular myosin heavy chain, type B; Myosin heavy chain 10; Myosin heavy chain, non-muscle IIb; myosin heavy chain, nonmuscle type B; myosin, heavy chain 10, non-muscle; myosin, heavy polypeptide 10, non-muscle; myosin-10; NMMHC II-b; NMMHCB; NMMHC-B; NMMHC-IIB; Non-muscle myosin heavy chain B; nonmuscle myosin heavy chain IIB; Non-muscle myosin heavy chain IIb; nonmuscle myosin II heavy chain-B
Description (eCommerce)
Myosin II is a hexameric protein that consist of a pair of heavy chain subunits (MHC), a pair of essential light chain subunits (MLC), and a pair of regulatory light chain subunits (RLCs). Non-muscle myosin heavy chain II-B is encoded by the myosin heavy chain 10 gene (MYH10) and non-muscle myosin heavy chain II-A is encoded by the Myosin heavy chain 9 gene (MYH9). Myosin in non-muscle cells is involved in motile cellular processes which include cytokinesis, cell shape, secrection, and capping.
Description (Vector)
MYH10 encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin; it should not be confused with the unconventional myosin-10 (MYO10). Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene have been associated with May-Hegglin anomaly and developmental defects in brain and heart. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
4628
Gene Name (eCommerce)
myosin heavy chain 10
Gene Name (Vector)
myosin heavy chain 10
Gene Symbol
MYH10
HGNC ID
HGNC:7568
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
5958
ORF Size (bp)
5958 bp
Protein Name (eCommerce)
Myosin-10
RefSeq ID
NM_005964
RefSeq Synonyms
NM_005964, NM_001256095, NM_001256012, BC150634, BC144668, BC117691, BC117690,
Research Areas
Axon Guidance,Cardiac Development,Cardiology,Cardiovascular,Cell Cycle,Cytoskeleton,DNA Damage/Repair,Host-Virus Interactions,Neurobiology,Neurodevelopment
Research Areas (Faceted)
cardiovascular,cell_biology,cell_cycle,genetics,transcription_translation,infectious_disease,neurobiology,developmental_biology
Species
human
Target Sentence
Myosin II is a hexameric protein that consist of a pair of heavy chain subunits (MHC), a pair of essential light chain subunits (MLC), and a pair of regulatory light chain subunits (RLCs). Non-muscle myosin heavy chain II-B is encoded by the myosin heavy chain 10 gene (MYH10) and non-muscle myosin heavy chain II-A is encoded by the Myosin heavy chain 9 gene (MYH9). Myosin in non-muscle cells is involved in motile cellular processes which include cytokinesis, cell shape, secrection, and capping.
UniGene ID
Hs.16355
UniProt ID (eCommerce)
P35580

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.